Home Blog Page 3

Why Early Imaging Insights Can Lead To Better Oncology Trial Endpoints

Why Early Imaging Insights Can Lead To Better Oncology Trial Endpoints

Oncology drug development is a complex, high-stakes endeavor where every decision can significantly impact the success of a clinical trial. One critical factor in improving outcomes is the ability to gain early and accurate insights into how a treatment affects tumors and their microenvironment. Advanced imaging techniques, especially when applied early in oncology trials, offer a powerful way to gather this information. Early imaging insights can lead to better-defined trial endpoints, more efficient trials, and ultimately, faster paths to regulatory approval and patient benefit.

The Challenge of Oncology Trial Endpoints

Endpoints in oncology trials serve as benchmarks for assessing a treatment’s effectiveness. Traditional endpoints include overall survival (OS), progression-free survival (PFS), and tumor response rates based on size reduction, typically evaluated by criteria like RECIST (Response Evaluation Criteria in Solid Tumors). While these endpoints are essential, they have limitations:

  • Long timelines: OS and PFS often require extended periods of follow-up before definitive conclusions can be drawn.
  • Indirect measures: Tumor size changes do not always reflect biological activity or treatment impact on the tumor microenvironment.
  • Heterogeneity: Tumors and patient responses vary widely, complicating clear endpoint assessment.

Incorporating early imaging insights can address many of these challenges by providing a more immediate and biologically relevant readout of treatment effects.

Why Early Imaging Matters

Early imaging techniques involve using advanced modalities such as PET (Positron Emission Tomography), MRI (Magnetic Resonance Imaging), and CT (Computed Tomography), often enhanced with molecular imaging agents, to detect changes in tumor biology soon after treatment initiation. Here’s why these early insights are game-changing:

  1. Faster Decision-Making: Early imaging allows researchers to identify responders and non-responders quickly. If a treatment shows biological activity early on, it justifies continuation and further investment. Conversely, lack of early effect can prompt trial adjustments or termination, saving time and resources.
  2. More Sensitive and Specific Data: Modern imaging can measure metabolic changes, blood flow, hypoxia, and other biological parameters that precede size reduction. This sensitivity helps detect subtle but meaningful treatment effects, leading to better characterization of the therapeutic mechanism.
  3. Personalized Treatment Approaches: Imaging biomarkers can reveal heterogeneity within and between tumors in a patient, enabling tailored treatment strategies and adaptive trial designs that improve patient outcomes.
  4. Improved Endpoint Validation: Early imaging biomarkers can serve as surrogate endpoints, predicting long-term outcomes like survival or durable response. This correlation enables faster regulatory decisions and can accelerate drug approval.

Real-World Examples of Early Imaging Impact

Several oncology trials have demonstrated the value of early imaging insights:

  • Immunotherapy Trials: Traditional endpoints often fail to capture the delayed or atypical response patterns seen with immunotherapies. Early PET imaging using metabolic tracers can distinguish pseudo-progression (initial tumor swelling due to immune cell infiltration) from true progression, helping avoid premature trial termination.
  • Targeted Therapy Trials: Imaging can reveal early metabolic shutdown in tumors targeted by specific inhibitors, even before anatomical changes appear. This early indicator can guide dosing and combination strategies.

Implementing Early Imaging in Oncology Trials

To fully harness the power of early imaging, clinical trial designers must integrate imaging strategies thoughtfully:

  • Selecting Appropriate Imaging Modalities: Depending on the tumor type and therapeutic target, different imaging techniques provide the most relevant data. Molecular imaging agents that target specific tumor markers or metabolic pathways can offer unique insights.
  • Standardizing Imaging Protocols: Consistency in imaging acquisition, analysis, and interpretation is critical to ensure data reliability and comparability across trial sites.
  • Incorporating Imaging Biomarkers as Secondary or Exploratory Endpoints: While regulatory acceptance of imaging endpoints is evolving, including them early in trials allows for robust data collection and validation.
  • Partnering with Imaging Experts and Technology Providers: Collaborations with specialized companies that focus on preclinical and clinical imaging technologies can accelerate the integration of cutting-edge imaging into trials.

One such leader in this space is perceptive.com, which offers advanced preclinical imaging solutions that help researchers understand tumor biology and treatment responses at an early stage. Their expertise supports the development of reliable imaging biomarkers that can translate into clinical trial endpoints.

Future Directions and Innovations

The field of oncology imaging is rapidly evolving with new technologies that promise even greater insights:

  • Artificial Intelligence (AI) and Machine Learning: AI-driven image analysis can detect patterns and subtle changes invisible to the human eye, improving predictive power and endpoint accuracy.
  • Hybrid Imaging Techniques: Combining modalities (e.g., PET/MRI) provides complementary information, enhancing the understanding of tumor biology.
  • Liquid Biopsy Integration: Correlating imaging data with molecular markers from blood samples could offer a comprehensive picture of treatment response.

Conclusion

Early imaging insights hold the key to transforming oncology clinical trials by enabling faster, more accurate, and biologically relevant assessments of treatment efficacy. By incorporating these advanced techniques into trial design, sponsors can improve endpoint definition, reduce trial duration, and enhance the likelihood of success. The synergy of innovative imaging technologies and strategic trial planning is setting a new standard for oncology drug development, ultimately accelerating the delivery of effective therapies to patients in need.

Why You Should Stop Wearing Shoes Inside the House

A University of Arizona study found shoes can hold over 400,000 units of bacteria. Within just four steps indoors, those germs hit your floors—and can linger there for days.

Your floor might look clean, but how clean can it really be if you’ve walked through a gas station and then across your kitchen without stopping?

It might feel harmless, even polite, to leave your shoes on. But this small habit affects more than just appearances—it impacts your health, your space, and the way you feel at home.

Your Shoes Are Bringing in More Than Just Dirt

Think about where your shoes go. Public bathrooms. City sidewalks. Gas stations. Hospital parking lots. Your shoes pick up more than just visible grime—they collect bacteria, toxins, pollen, and even traces of fecal matter.

Research shows that the soles of our shoes are a magnet for harmful microbes. Nearly all tested pairs were found to carry coliform bacteria — including E. coli — along with countless other germs you’d never want inside your home. Picture them transferring from your shoes to your kitchen tiles, embedding in your carpets, and ending up right where your children or pets play.

If you have carpets, the issue gets worse. Bacteria and dirt get lodged deep in the fibers, making it much harder to remove. Every step you take inside with your shoes on is essentially grinding outside toxins into your home’s surfaces. If that visual alone doesn’t change your mind, maybe this will: those toxins don’t just sit there. They mix with household dust, circulate in your air, and contribute to respiratory irritation, especially if someone in your home has asthma or allergies.

In one study, researchers at Baylor University found that coal tar, a known carcinogen used in some asphalt driveway sealants, can be tracked indoors on the soles of shoes. Once inside, it becomes part of household dust—something young children are especially exposed to when they crawl or play on the floor.

Wearing Shoes Indoors Wrecks Floors and Raises Stress

Aside from health hazards, shoes indoors do real damage to your home. Hardwood and tile floors get scratched and scuffed. Carpets wear out faster and hold on to stains. Over time, this adds up to higher cleaning bills and more frequent replacements. But beyond the cost, there’s the quiet mental toll of mess. Clutter and dirt—even when we don’t consciously notice it—can impact our mood and focus.

Imagine walking barefoot across a clean, smooth floor. Now imagine stepping on a tiny rock that fell off someone’s shoe. One disrupts your calm. The other grounds you. Shoes bring in the static. Bare feet help you settle.

The Hidden Downsides No One Talks About

Not everything needs a scientific study. Some reasons are just plain obvious when you live with them.

  • Dirt spreads faster than you think and always ends up in the weirdest places
  • They pile up near the door and instantly make the space feel cluttered
  • Walking in with them makes it harder to mentally switch off and relax
  • Every step echoes if you’ve got someone living below you
  • Your pet probably sees them as fair game (especially the laces)
  • They keep your feet in “outside mode” when your home should feel like a reset

A Small Habit Shift That Pays Off

Here’s a simple test:

Would you sit on your kitchen floor after walking across it in your shoes?

Would you let a baby crawl there without wiping it down first? If the answer is no… maybe it’s the shoes.

Changing this habit doesn’t require anything dramatic. Start with a simple shoe rack or basket near your entryway. Place a small bench or chair nearby for guests to sit while they take off their shoes. Offer cozy indoor slippers or clean socks. These small acts signal hospitality, not inconvenience.

Families who adopt a no-shoes policy often report that their homes stay cleaner longer. 

Think of Your Home as a Sanctuary

Think of your home as more than just four walls—it’s your sanctuary. A place where your body rests, your mind resets, and the weight of the outside world doesn’t follow you in.

Shoes belong to the noise, the grit, and the rush out there. Every step you take without them inside is a quiet act of self-care.

So, trust your instincts. You already know your space feels better when it’s clean, calm, and free from what doesn’t belong. Listen to that voice. Protect it.

Take care.

Pause for a second-think of one person who’d love this. Got someone?

Great-now share it before you forget.

Sources:

  • Pew Research Center. How Americans View Remote Work – Trends in who works remotely, how often, and how workers feel about it. March 2023. https://www.pewresearch.org/short-reads/2023/03/30/how-americans-view-remote-work/
  • U.S. Bureau of Labor Statistics. American Time Use Survey – 2024 and 2025 data on working from home. https://www.bls.gov/tus/
  • Barrero, J., Bloom, N., & Davis, S. (2023). WFH Research – Survey of Working Arrangements and Attitudes (SWAA). https://wfhresearch.com/
  • Bloom, N., Liang, J., Roberts, J., & Ying, Z. (2015). Does Working from Home Work? Evidence from a Chinese Experiment. Quarterly Journal of Economics, 130(1), 165–218.
  • OECD. Productivity gains from telework during and after COVID-19. 2023. https://www.oecd.org/
  • Gallup. The Remote Work Paradox – Engagement, wellbeing, and hybrid trends. 2025. https://www.gallup.com/
  • CIPD. Flexible and hybrid working: Benefits for work-life balance, wellbeing, and recruitment. UK Parliamentary Evidence, 2025. https://www.cipd.org/
  • Eurofound. Telework and ICT-based mobile work: Flexible working in the digital age. 2022. https://www.eurofound.europa.eu/
  • International Labour Organization (ILO). Working from home: From invisibility to decent work. 2021. https://www.ilo.org/
  • U.S. Census Bureau. Who Usually Works From Home – 2025 Data. https://www.census.gov/
  • McKinsey & Company. American Opportunity Survey – Remote work access and inequities. June 2022. https://www.mckinsey.com/
  • Kate Lister, Global Workplace Analytics. State of Remote Work 2019. Owl Labs. https://www.owllabs.com/

Kids Smatch Watch: Real Solutions for Everyday Parenting

kids smart watch from Bark

One of the most underestimated jobs today is modern parenting. The management of different schedules with work and after-school activities can make the average citizen dizzy. Between work commitments, multiple children, and activities scattered across town, something always seems to go wrong. A meeting runs late, traffic backs up, or a child forgets about an early dismissal day.

When phones started being popularized, most parents were excited because a direct line to parents helps solve some daily headaches with child-rearing. However, it’s not all sunshine and rainbows because cellphones and other mobile devices have created some unforeseen consequences.

An Independence Tightrope

One of these consequences is the shift in childhood development, specifically regarding a child’s independence. Raising confident, capable children requires giving them opportunities to succeed independently. But safety concerns often prevent parents from allowing the kind of independence that builds character and problem-solving skills. Giving a kid a phone is a big milestone, but it can also be too much access to resources without enough oversight.

The Bark Watch is a middle ground that changes this equation by providing a safety net that doesn’t feel restrictive. Children can walk to school, play at friends’ houses, or explore their neighborhood while parents maintain appropriate awareness of their whereabouts through a kids’ smart watch. A kid’s smart watch from Bark creates space for healthy independence without ignoring legitimate safety concerns.

The Screen Time Struggle

Parents today face constant battles about screen time limits. Children want more access to devices, while parents worry about addiction, inappropriate content, and the impact on development. Traditional parental controls often feel like a game of cat and mouse, with children finding ways around restrictions.

The kids’ smart watch sidesteps this entire conflict by providing limited, purposeful technology access.

Children can’t spend hours scrolling through videos or playing games, but they can still communicate when needed. The device satisfies the desire for personal technology without creating the problems that come with unlimited access. Smaller screens mean fewer arguments about screen time after switching to a kids’ smart watch because the device simply doesn’t offer the endless entertainment that creates conflicts with traditional smartphones or tablets.

Connection with Peace of Mind

Whether it’s the first day of school, a sleepover, or time spent with a babysitter, parents and children can both experience stress during separations. The kids’ smart watch helps ease these transitions by providing a communication bridge that reduces anxiety for both parties. Children know they can reach parents if needed, and parents can check in without being intrusive. Connection with a kids’ smart watch can give children the confidence to try new activities and spend time away from home. Parents typically feel more relaxed about work travel, date nights, and other separations when they know that their children have a reliable way to reach them.

Other Features of the Bark Watch

The Bark Watch tackles parenting challenges through several key features that work together to create a safer, more connected experience for families.

Curated Contact List: The Bark Watch keeps communication simple with calling and texting capabilities that parents control completely. Children can only contact people on their approved list, which eliminates worries about strangers or inappropriate contacts. This controlled approach lets kids stay connected with family and close friends without opening the door to broader online risks.

Advanced Location Tracking: Real-time tracking gives parents information about where their children are throughout the day. The geofencing feature sends automatic alerts when kids arrive at or leave designated areas like school, home, or a friend’s house. This removes the guesswork from busy schedules and provides peace of mind during transitions.

AI-Powered Content Monitoring: Flagging concerning messages, photos, or interactions is done automatically using AI-powered tools. Parents get alerts about potential issues like bullying or inappropriate content without having to review every message. This approach protects children while respecting their growing need for privacy.

Emergency SOS: While emergency scenarios may be difficult to face, having a panic button gives children a direct line to call for help when they need it most. This feature provides crucial protection during genuine emergencies while giving children confidence to explore their world.

Protect Your Household with Bark

Rather than viewing the Bark devices as just another piece of technology, parents can see it as a tool for addressing specific challenges that arise in contemporary family life. A kids smart watch from Bark provides controlled access to communication technology while protecting children from the potential negative impacts of unlimited device access.

For families dealing with the daily stress of coordinating schedules, managing multiple children, and balancing work and family commitments, the kids’ smart watch offers relief from many common sources of anxiety and miscommunication. Learn more about Bark Technologies and protect your household today.

Talking Tactics: How Shared Sportsbook Analysis Can Boost Your Communication in Relationships

How Sportsbook Analysis Can Boost Your Communication in Relationships

Do you want to find something unusual to improve communication in your relationships? Whereas conventional wisdom revolves around date night, a surprising new strategy has been discovered: mutual online sportsbooks. With a cooperative attitude behind it, this exercise becomes a lively joint endeavor in which partners can enhance their communication and become closer. Collaboration enables partners to explore and analyze data, after which they make joint decisions, thus creating trust between them and honing problem-solving skills. This unusual, but efficient, approach to connecting is a good enough indication that responsible play has the potential to become an effective stimulator of a better, more communicative relationship.

The Foundation: The Power of Shared Hobbies

It is essential to have a common hobby to develop a healthy and fulfilling relationship. Research findings are consistent that couples who spend time engaged in activities together report more relationship satisfaction and a greater sense of we-feeling. Such everyday experiences are essential for constructing the common past and developing a strong bond. The ideal hobby establishes a casual environment of self-effectively free communication, and ease of emotional intimacy, including inclusion, making things interesting, and working together. Teamwork and mutual problem-solving also help partners better understand each other, building a stronger pillar to the partnership. This habit will lower stress levels, enhance life satisfaction, and prolong the frisson because you will have a fresh and exciting look at your partner.

The Sportsbook as a Catalyst for Communication

So, what are some ways in which it is possible to reframe the world of sportsbook odds analysis as a dynamic communication tool? Adopted in a joint venture format, the research, discussion, and the imposition of bets on a sporting event become the fertile ground onto which it is possible to lay and nurture all critical interpersonal skills.

1. Shared Goals & Collaborative Problem-Solving

In essence, the analysis of sportsbook odds used by everyone has one unifying goal: the ability to offer adept forecasts and the hope that it will be successful. This common purpose instantly puts them into a team spirit. It is no longer a case of deciding by any one person; it is an issue of two brains trying to assemble a highly complex piecework puzzle.

  • Joint Analysis: Both partners are charged with evaluating a variety of aspects: team build-up, injury of players, the match report, coaches’ tactical approaches, and even weather factors. This will require the efforts of both parties.
  • Discussion and Debate: The analysis is not in silence. It requires talk and talk, conversation and debate, and the exchange of ideas. One partner can emphasize a statistical peculiarity, whereas the other will note the psychological advantage. This give-and-take is what constitutes problem-solving, and this is where various sides of the argument are presented and evaluated.
  • Simulating Real-Life Challenges: In a recreational environment where there is control, couples will have to make a decision that will have a physical result. This will resemble a real-life problem-solving situation in which they are able to practice their collaborative decision-making capability without the stakes of making an important life decision.

2. Mastering Data Analysis and Information Sharing

Specific betting is an activity that requires information gathering, and this makes both couples bond through this process.

  • Bringing Individual Research: Each partner may conduct their own investigation and pay attention to various sources or elements of a game. When they meet, they will have to express very clearly what they found and the reason why they reached their conclusions.
  • Articulating Complex Information: The ability to explain, succinctly, the failure of a particular team to have a defense or the poor form of a player is a skill that requires clarity and conciseness. This habit enhances the capacity to clarify complex ideas in a perspicuous manner.
  • Active Listening: Listening is just as essential as speaking. This involves partners listening to each other so that they can comprehend the other party’s perception, regardless of whether it opposes theirs. This is done by asking questions to clarify the point and paraphrasing to understand. This can be seen as practicing to listen better in every aspect of the relationship.

3. Practicing Respectful Persuasion and Negotiation

During the analysis of possible bets, partners are bound to disagree. This gives a natural space to exercise respectful persuasion and bargaining.

  • Expressing Confidence and Doubt: One party may have a lot of confidence about one outcome, and the other party may express doubts about the same outcome. It is essential to learn how to express these feelings and the reasons that are the causes of these feelings.
  • Justifying Reasoning with Evidence: Rather than stating, “I think Team A will win,” the partners must learn to say, “I think Team A will win because their offense has been especially effective against zone defense, and their opponent is running a zone.” This is a practice in evidence-based reasoning, which strengthens arguments and makes it easier to be more logical in discussions.
  • Agreeing, Disagreeing, and Compromising: Not all bets will go unanimously. Couples have to know how to respectfully agree or disagree constructively and where they can reach an acceptable compromise. This negotiation skill is very practical in day-to-day relationship situations.

4. Navigating Risk and Decision-Making Together

Risk is involved in the activity of placing a bet. Sharing and discussing this risk openly is a good opportunity to know the other person’s comfort zone and decision-making preferences.

  • Discussing Potential Outcomes: Couples talk before betting about the best and worst that could occur. This kind of foresight helps regulate expectations.
  • Jointly Deciding on Stake Size: What is your comfort level with betting? Such discussions bring out individuals’ risk tolerances and require a consensus.
  • Pre-Agreed Strategy for Wins/Losses: Before a couple goes the extra mile in a spouse relationship, they should devise a way of handling their wins and, more importantly, their losses. This pre-planning will avoid arguments, and both will be in agreement.

5. Building Emotional Regulation and Resilience

The sports betting world is emotional, as victory leads to the highs and defeat to the lows. The learning process of these feelings can make the relationship more resilient and empathetic.

  • Managing Excitement and Disappointment: When a bet hits, the shared excitement is a powerful bonding agent. When it doesn’t, learning to manage disappointment without blame is vital.
  • Providing Support and Empathy: Following a defeat, a nice partner could say, “It was unfortunate, but we had a good analysis.” This develops sympathy and makes them understand they are a team, whether winning or losing.
  • Avoiding Blame: The most treacherous trap is attributing a losing bet to someone or something. Emphasis must always be on the process and joint decision, not personal wrong.

Practical Steps for Success: The Importance of Responsible Play

The couple must have a structured and responsible way of utilizing collective sportsbook analysis as a communication booster. This is not to encourage gambling, but to use a particular activity as a positive interaction framework.

A. Establish Ground Rules (Crucial)

This is the most crucial part. Without clear boundaries, fun activities can quickly become stressful.

  • Set a Strict, Non-Negotiable Budget: This fun money ought to be a sum that you feel comfortable putting at risk and that would not affect the necessary finances. Consider it entertainment spending, such as going to the movies or having dinner out.
  • Agree on Time Limits: Decide on how much time you would like to spend on analysis and betting. This will help ensure that the activity does not take up much of your time.
  • Emphasize Fun and Connection: You should never forget that the primary purpose of all this is to spend time together, communicate, and have fun; it is not to make money.

B. Choose Your “Game” (Sports/Leagues)

It should be an activity that captures the interest of both partners, and it is better when both of them have at least some interest in the sport.

  • Pick a sport you Both Enjoy: Begin with a sport you are both interested in, even marginally. The common interest is a natural point of origin of a conversation.
  • Be Open to Learning: When one partner is crazy about a kind of sport and the other does not know much about it, there is a chance for teaching and learning. The more understanding partner can share the details, and the less informed partner can ask questions and learn more about the sport and their partner, and the things that they love.

C. The “Analysis Date Night”

Make the process of analysis a focused and fun group business.

  • Dedicated Time and Space: Designate a specific time, maybe once a week or before a big sporting event, and dedicate that time to sportsbook analysis.
  • Focused Conversation: Another thing to do during this time is to make it a rule to have few distractions. Leave those phones aside (except when needed during the research), and concentrate on what we are doing and on one another.
  • “War Room” Vibe: Make it enjoyable. You may have snacks, a delicious drink, and a whiteboard to note any stats or predictions. This makes the analytical process feel like a special united process.

Beyond the Bet: Transferable Communication Skills

Boost your relationship with shared sportsbook analysis! It is no longer simply a means to a possible win, but an excellent communication performance tool to grow your relationship. Talking about betting gives couples a chance to learn active listening and understand each other without waiting to speak. Low-stakes culture perfectly applies to learning constructive disagreement, where you can politely express various points of view and identify the middle ground. More so, decision-making on mutual betting helps instill a sense of togetherness, shared responsibility, and accountability since both parties own the outcome. Building a relationship with your partner through betting together will help transform it.

The Soul of Business: An Interview with Kenneth W. Welch Jr. On Spiritual Entrepreneurship – Its Meaning and Its Change

Spiritual Entrepreneurship

“Never compromise core values for profits alone – it limits the full potential seeded in any venture aligned to higher purpose,” declares iconic CEO Kenneth W. Welch Jr. By profoundly fusing spirituality with entrepreneurship, this consummate visionary manifests enterprises as catalysts for global good and profit, in three distinct forms.

By perceiving spiritual entrepreneurship in terms of, care for the People of Earth, care for Mother Earth herself and the creation of financial gain and growth potential for the company, to create a legacy corporation.

Through his marketing trailblazer firm Moxie Media, world-changing ventures like Global Oceanic Designs, and his vision of the “Harmony of Generations” mega- concert concept, Welch illuminates the pathway of the “soulpreneur.”

I recently asked him to share wisdom on uplifting both revenue and consciousness through spiritual business principles, aimed at Mother Nature and Civilization itself, as we forge into our Future Generations’ existence on Earth.Image of Kenneth W. Welch Jr.

Manifestation Magnifies Meaning and Money

“Manifestation is key to call in critical resources, vitalize startups, as well as setting visions aflame with deeper soul purpose,” Welch begins. “Assuming an “abundance”, versus “lack”, state of consciousness, I could focus on building ventures uplifting humanity, as opposed to fixating on chasing capital, simply for personal growth.” This foundation of trust in the universe freed Welch to flow through inspired action more so than reactive hustling, when he started focusing on the greater good, and the overall abundance, not only for himself, but for all, Mother Nature, the corporation’s structure and personnel and the future visions of its growth potential and involvement going forward.

In tandem, Welch also notes the importance of clarity when setting intentions for new enterprises. “Getting specific on how my companies can positively impact people, multiplies manifestation momentum. Those visions, rooted in helping humanity, then magnetize supportive conditions, effortlessly.”

Surrender and Flow

Yet even the most resonant intentions hit walls without flexibility, per this seasoned founder. “All entrepreneurs must surrender to mystery, engage curiosity, and expect continuous change, as the only constant when building, because nothing is constant!  Change, in so many forms, such as the constant effects of weather and natural disasters, and many other embodiments, all acting as factors within, and affecting, this flowing creative endeavor”, Welch acknowledges. He accepts the natural entrepreneurial journey as an ever-unfolding creation, requiring intuition-fueled adaptability, versus rigid attachments. “By getting ego out of the way, you allow wisdom far beyond your limited ideas to guide ventures into growth and greatness, uniting the collective, helps provide for global change on a mass scale.”

Seeds of Success

For Welch, leaning into faith also eases the burden of building high-impact companies as a solo effort. He elaborates, “I perceive my role more like a global gardener versus a local construction worker – tending seeds versus forcing outcomes, on an international scale. When you foster the organic conditions for growth, through care and trust, exactly what needs to emerge manifests itself in the collective, as the projects evolve and expand in succession, due to the collective efforts of a vast community of talent and creativity, with focus, determination and meaning.”

In the entrepreneurial garden of Moxie for example, Welch focuses on nourishing the universal values of integrity, creativity, and positive social change to flower freely, as ideas, concepts, innovations and inspirations. The natural fruits in turn became runaway sensations, like his efforts to support and promote the independent artists and creators performing on TikTok, by providing them with backbone support, in their hopes to stand alone, in such a vast global market, of diversified talent.

Limiting Beliefs Get Left Behind

Of course, in trailblazing new territory, expanding beyond convention, doubt and obstacles arise. Yet limitations cannot take root in the fertile spiritual soil of intention, Welch recommends cultivating, garnering creativity through expansion and by embracing collective growth.

“I simply ask, ‘how can this challenge become a catalyst for even greater expansion and effect?’ Then inspired innovation follows, as higher forces ignite unforeseen possibilities, reimagined, invented, created or perceived.

Unity Consciousness = Shared Success

Finally, this luminous CEO stresses that spiritually oriented business is always mutually beneficial business. “When my focus stays on cooperation versus competition – creating for the wellbeing of both humans and nature – that win-win intention ripples outward through aligned actions and offerings,” he observes, as a collective whole.

Accordingly, Welch configures his most conscious corporations like Global Oceanic Designs, set on future technologies, sustainable building materials, futuristic designs, featuring longevity and sustainability, a plethora of new systems and designs, from underwater living to transportation, to securing the food supply, providing habitation, etc.… to operate through a lens of interdependence with society and nature. “We share solutions benefiting as many groups as possible, knowing our success depends on empowering others to thrive, vibrantly within these new directions, ideas, technologies and concepts.”

This cycle of social value uplifting new markets, versus pursuing narrow self-serving gain, manifests prosperity no single agenda could attain. For trailblazers like Welch therefore, leaning fully into uniting higher purpose with business, builds not only fortune – but fulfills transformation, providing legacy and a better future for a symbiotic relationship between our people and our planet.

3 Must-Know Technical Indicators for Forex Traders

3 Must-Know Technical Indicators for Forex Traders

Whether you’re a relatively new forex trader or already executing trades with practiced precision, one thing’s for sure – you need solid tools for the journey. One of these tools is technical indicators that turn data into actionable insights.

These indicators are essential for helping traders identify trends, entry and exit points, and potential market reversals. But with a wide range of options out there, how do you know which ones are actually useful?

Here are three must-know technical indicators to help your forex trading journey.

1. Moving Averages

Moving averages smooth out price data to help you identify the overall direction of the market. There are two types of moving averages that can be used in Forex trading.

One is the Simple Moving Average (SMA), which shows the average price over a set number of periods; and the other is the Exponential Moving Average (EMA), which gives more weight to recent prices, making it more reactive. Now, let’s say you’re keeping your eyes on the EUR/USD pair. If the current price is above the 200-day SMA, that’s generally a bullish signal, meaning the prices are likely to rise. Combine that with short-term EMA, and you’ve got potential confirmation of a long-term uptrend.

You can use moving averages to identify trend direction, as support/resistance levels, and in crossover strategies. Also, EMAs are especially useful in fast-moving markets like forex. Many traders use the 9 EMA and 21 EMA for short-term strategies.

2. Relative Strength Index

The Relative Strength Index (RSI) is a momentum oscillator that ranges from 0 to 100 and tells you whether a currency pair is overbought or oversold. If it’s above 70, it’s likely overbought, while below 30 indicates oversold. Markets don’t go up or down forever. RSI helps you spot when things are getting overheated or too beaten down, also called potential reversal zones.

You can use RSI to spot trend reversals, confirm price movements, and catch divergence between RSI and price. For instance, if one currency pair is surging but RSI drops, it could mean the momentum is fading – even if the price is still climbing. That divergence may be your sign to tighten stop losses or exit the trade.

3. Moving Average Convergence Divergence

The Moving Average Convergence Divergence (MACD) is like a combination of moving averages. It tracks the relationship between two EMAs and shows signals about trend direction, momentum, and potential reversals.

The MACD has a MACD line, a signal line, and a histogram showing the difference between the two. It’s like getting three tools in one as you can use it to confirm trends, track momentum, and signal entry or exit points.

When the MACD line crosses above the signal line, it’s a sign of prices rising. Looking at the histogram, when the bars grow, it means momentum is increasing. Similarly, when they shrink, assume that the momentum is fading.

Just like with RSI, if price and MACD move in opposite directions, stay cautious and alert. If you notice the MACD histogram shrinking, it might be time to step back and reassess – or take profits and run.

Conclusion

Technical indicators are far more than visual aids—they’re the foundation of informed, confident trading in the fast-paced world of forex. Whether you’re just stepping into the market or already charting your course with finesse, using tools like Moving Averages, RSI, and MACD gives you clarity amid volatility.

Each of these indicators brings a unique lens through which you can interpret market behavior, identify strategic entry and exit points, and better manage risk. But the key isn’t just using them—it’s learning how to integrate them into your trading plan, cross-verify signals, and adapt as conditions evolve.

The forex journey is full of variables, but with strong analytical tools and consistent practice, you’re not just reacting to price movements—you’re predicting them with precision. Equip your strategy with these indicators, and you’ll trade not just with numbers, but with insight.

The Science Behind T-Shape Technology

T-Shape Technology

Have you been looking for something to correct your imperfections, improve tissue elasticity and fight excess fat? T-shape technology provides all this and more! This contouring tool provides the power of cutting-edge aesthetics to you. The best part is that t-shape technology is actually backed by science.

What are Body Treatments, and What Different Types Are There

The purpose of a body treatment is to improve the appearance and health of your body and skin. There are a wide variety of body treatments available, including:

  • Dry brushing
  • Body sculpting
  • Massage
  • Body scrubs
  • Body masks
  • Body wraps
  • Facials
  • Hydrotherapy
  • Aromatherapy
  • Manual lymphatic drainage
  • Reflexology

For example, a body scrub will remove your dead skin cells through exfoliation. Materials such as salt, coffee grounds or sugar are used throughout this process. Once your body treatment is complete, you can expect to see smoother skin.

Another prime example is body sculpting, which sometimes uses t-shape technology. It includes the innovative usage of technology to tighten, tone and improve the appearance of a specific spot or area of skin.

What is T-Shape Technology?

T-shape technology is a painless method for targeting localized fat deposits. This is done by encouraging collagen production, which results in a reduction of skin laxity and adipose volume. The specific area you use t-shape technology on receives a physical boost. How does this happen? Through lymphatic drainage and boosted blood circulation.

T-shape 2 uses four specific things to make your skin look its best. These include:

  • Low-level laser therapy – Supports skin regeneration and healthy blood flow.
  • Vacuum suction – Boosts oxygen flow and circulation to tighten and lift your skin.
  • Bipolar radio frequency – Tightens and lifts your skin by stimulating your body’s natural collagen production.
  • Mesospheric deep massage – Enhances your overall wellness by promoting balance and relaxation.

The Benefits of T-Shape Technology

Achieving a t body shape may take six to 12 sessions, but it’s worth it once you consider all the benefits of using t-shape technology.

  • Non-surgical treatment.
  • Much more affordable than plastic surgery.
  • No downtime is needed.
  • Non-invasive, comfortable treatment.
  • Boosts abdominal muscle thickness.
  • Firmer skin.
  • Reduces excess fat.
  • Micro-vibrational massage helps relieve minor muscle pain.

Going under the knife for plastic surgery means you’ll miss at least one week of work. Additionally, you’ll have swelling and bruising for up to a month. Overall, you can expect to need three to six months before receiving the full benefits of your surgery.

Meanwhile, undergoing a t-shape 2 treatment takes approximately 30 to 75 minutes. As soon as your treatment ends, you’ll be free to return to your normal, daily activities.

Who is T-Shape 2 Right For?

T-shape 2 is right for men and women. It provides a non-invasive, natural treatment for those who don’t want to face the downtime that’s associated with plastic surgery. Whether you’re dealing with stubborn fat or want to smooth and reduce your cellulite, getting a t-shape treatment can help!

Have you tried other body treatments without receiving the desired results? T-shape 2 may be right for you. Take advantage of this contouring tool to help you look and feel better. To schedule your t-shape appointment or to ask more questions, reach out to Cloud 9 Aesthetics today.

Functional vs. Traditional Medicine: What’s the Difference?

Functional vs. Traditional Medicine

We get it: you may not be enthusiastic about traditional medicine. However, traditional medicine is not the only type of medical help that you can consider as a patient. Specifically, while integrative medicine addresses the whole person rather than just the disease, another type of medicine has gained popularity in recent years: functional medicine. Similar to integrative medicine, it strives to treat the holistic individual, while also paying close attention to internal and external environmental factors. In this article, we explore the difference between functional and traditional medicine, the benefits of each and whether or not you should have a functional and traditional medicine doctor.

What Is Functional Medicine?

Functional medicine focuses on a holistic, deliberate approach to treating patients. Rather than keeping the focus on the disease and the traditional treatment for it, functional medicine takes a patient’s environment, lifestyle, family history and other factors into account. Simply put, a functional medicine doctor strives to investigate and address the fundamental root causes of the condition. As an example, if you are diagnosed with heart disease, your functional medicine doctor will try to support a reduction in your stress levels, advise you to begin an exercise program, and develop a healthier diet.

Is Functional Medicine Legit?

Research has demonstrated that functional medicine is not only legitimate, but can be a highly beneficial form of patient care. Specifically, a family health center conducted a study with 7,252 patients. One portion of this group was treated with functional medicine. The other group was treated with traditional medicine. The results demonstrated that the group that received functional medicine felt better after six months than the other group.

The fact that functional medicine is grounded in evidence-based research has created more and more momentum in its external perception as a legitimate form of medical care.

Integrative Medicine vs Functional Medicine

There are more similarities between integrative medicine and functional medicine than there are differences. In both cases, practitioners use diet and nutrition to fight long-term diseases. They both treat the patient as an individual with their own history, personality and lifestyle. The medical community also agrees that both these types of medical approaches are “alternatives.”

There are also a few differences. Functional medicine uses blood tests, genetic testing and allergy testing in its practice. Integrative practitioners do not necessarily use these tests. Instead, the practitioner focuses on the mind-body combination. They are also less in favor of recommending invasive treatments and medications that are not “natural.”

How to Find a Functional Medicine Doctor

You understand the difference between functional medicine and traditional medicine, its benefits, as well as its similarities to integrative medicine. Now, you are ready to find a functional medicine doctor that suits your specific needs. Where does one begin? As functional medicine is a current buzz-word in the medical world, there are many individuals trying to capitalize on its trend, without the necessary training to validate their claims. Therefore, begin by researching for board-certified functional medicine doctors in your area. Whether you’re looking for a functional medicine doctor in Chicago, New York City, Los Angeles, or any other city, the difficulty is not finding one, but rather, practitioners that are MDs and hold a certificate at the rigorous Institute for Functional Medicine.

Dr. Rajka is a functional medicine doctor Chicago with a practice right in your location. She will find the root causes of your medical condition and then develop a treatment plan that leads you toward good health in the long term. Visit the link and set up a consultation today.

Emerging Online Food Ordering Trends in 2025

Online Food Ordering Trends to Watch in 2025

Online food ordering isn’t just a convenience anymore—it’s a essential. The way people choose, order, and receive their meals has changed more in the last five years than it did in the prior two decades.

And if 2025 is any indication, there’s still plenty of evolution on the way.

This guide breaks down the biggest online food ordering trends restaurants and food businesses should watch right now. Some are tech-heavy, some are just smart business. Either way, if you’re in the food game, you’ll want to know what’s coming next.

1. Smarter Ordering with AI Is No Longer Just Optional

It’s everywhere — AI in food ordering isn’t just a buzzword. Restaurants are using it for everything from menu recommendations to order prediction. AI looks at past customer data (like what someone ordered on Fridays at 7 pm) and uses it to recommend dishes or even nudge them with smart promotions.

And here’s the kicker: smaller restaurants are getting into the game too. You don’t need to be a massive chain to use AI anymore. There are companies out there offering AI powered and versatile restaurant automation solutions that are scalable at affordable prices.

2. Restaurants Want Their Own Turf Back

There’s a growing trend of ditching the middleman. More restaurants are investing in first-party ordering systems instead of relying solely on apps like Uber Eats or DoorDash.

Why?

Because owning the customer relationship is gold. First-party platforms mean you get to keep the data, set your own rules, and avoid those painful commissions that can go high as 30%.

These new trends in online food ordering reflect a bigger push toward brand control.

3. Ordering by Voice or Text? That’s Happening

This one’s flying under the radar a bit, but expect it to go big. Voice-based ordering —whether it’s through Alexa, Google Assistant, or even WhatsApp chatbots — is becoming smoother and faster.

People already use voice to order groceries, book rides, and check the weather. So, it makes sense they’d start saying “Order my usual from Joe’s Pizza” and expect it to happen.

This is part of the broader shift to conversational commerce, and it’s only going to grow in 2025.

4. Delivery & Takeout? Still King

Dine-in isn’t dead, but let’s face it — delivery and pickup have stayed dominant, even after COVID restrictions faded. That trend is holding strong in 2025.

What’s changing is the experience. Customers want accurate delivery times, driver tracking, and easy pickup lanes. That means restaurants need tech-driven logistics to stay competitive. It’s not just about cooking fast—it’s about delivering smart.

5. Syncing Online Orders with the Kitchen Matters More Than Ever

Here’s where things often break down: someone places an online order, and it never hits the kitchen right.

Sound familiar?

More restaurants are realizing that their 1st and 3rd party online ordering platforms and other kitchen tech needs to be able work in sync.

6. Subscription Models & Tailored Discounts Are Catching On

It’s not just about loyalty points anymore. Customers want to feel like brands “get” them.

In 2025, expect to see more hyper-personalized offers — like discounts on your usual Friday order or free delivery for your favorite item.

Also popping up: subscription models. Think $9.99/month for unlimited free delivery or early access to new menu drops. These models are especially popular among fast-casual spots and repeat customers.

7. Sustainable Choices Are Part of the Decision

People want to know:

Is this takeout bag recyclable?

Where’s this chicken from?

Restaurants that offer clear sustainability and sourcing info are gaining trust and orders.

Many platforms now include eco-friendly badges, carbon impact estimates, and compostable packaging options at checkout. These are more than nice-to-haves; they’re a core part of what some customers look for when choosing where to order.

8. Ghost Kitchens & Virtual Brands Keep Gaining Ground

Call it a kitchen without walls. Ghost kitchens are growing rapidly because they allow restaurants to test new menus, expand delivery zones, or run side brands—all without opening a physical location.

They’re also behind the boom of virtual restaurants—brands that only exist online, but still serve real food. Expect more experimentation here, especially in urban areas where rent is high and competition is tighter than ever.

9. Customers Want Control Over Their Data

Lastly, a quiet but important trend: data transparency.

People are starting to ask how their data is being used.

What are restaurants tracking?

Can I opt out?

Expect more ordering platforms to include cookie preferences, data-use summaries, and opt-in personalization toggles. It’s not just about privacy laws—it’s about building customer trust.

Conclusion

There’s no denying it: the online food ordering trends shaping 2025 are deeply tied to tech, personalization, and smarter operations. Whether it’s faster checkouts, AI-driven ordering, or fully virtual kitchens, the industry is moving quickly and restaurants that don’t keep up will fall behind.

The good news?

Most of these tools are accessible now, not just to the giants. With the right setup, even small restaurants can take advantage of the trends in online food ordering and build lasting customer relationships.

The Illusion of Control: Why We Think We Can Outsmart the Casino

Casino

You step onto the casino floor, heart racing as you approach the nearest machine. You tap the button—again and again—convinced that this time you’ll call the perfect moment.  

But deep down, you might sense something off. That feeling of agency? It’s a beautifully crafted illusion. 

The Power of Rituals (and Touch) 

Have you ever noticed how gamblers polish their lucky coin or jiggle the dice just so? Those little habits—rubbing the slot handle, choosing “hot” numbers—feel comforting. There’s a certain satisfaction in physical interaction, right?  

Turns out cognitive psychology shows that tactile engagement boosts our perception of control. When we feel in charge of the action, we’re more willing to keep playing. 

And it’s no accident. Designers know exactly how to harness this. Haptic feedback—vibrations, weighted levers, and clicky buttons—intentionally mimics skill-based games to reinforce our sense of mastery. These features are even found in modern slot machines, making us believe our choices shift the odds. 

Near-Misses: The Almost-Win That Hooks You 

You’ve seen it: two cherries line up, and the third perches just off the payline. That jolt of “so close!” isn’t disappointment—it’s engineered excitement.  

Researchers have demonstrated that near-miss events light up the same reward centers in the brain as actual wins. One study suggests near-misses can boost the likelihood of another play by up to 30 percent. It’s a phantom win, signaling your brain that success is right around the corner. Spoiler: it may not. 

Stop Buttons and Pseudo-Choices 

“Hit stop!” the screen seems to whisper as the reels whirl. Pressing that button feels strategic, like sniping the moment luck swings your way.  

In reality, the outcome was set the instant you spun. Yet, the stop feature feels interactive, personal—even powerful. It’s a classic “pseudo-choice,” a neat trick to deepen immersion without shifting a single probability.  

Why We Believe We’re Outsmarting the House 

Let’s be honest: casinos aren’t just about games—they’re about storytelling. We weave narratives around our wins and chalk up losses to bad timing. It’s human nature to want patterns, meaning, and above all, control. Cognitive biases like the gambler’s fallacy—thinking a roulette wheel is “due” for black after a streak of reds—keep us enthralled.  

Here’s a reality check: nearly 44% of American adults visit a casino at least once a year, drawn by the illusion of strategy and skill. This number hint at how powerful this illusion can be. 

Breaking the Cycle  

Awareness is your greatest ally. Recognizing that every “choice” in a casino game is carefully orchestrated can help you detach. Next time you hear the chime of a near-win or feel the thrill of pressing stop, pause.  

Is it truly your skill—or a design meant to draw you closer?  

At the end of the day, the house doesn’t rely on a single feature. It layers haptic feedback, visual cues, near-misses, and pseudo-choices to weave the illusion of control. Understanding these levers frees you to enjoy the spectacle—without letting it take hold. 

What’s your experience with that sense of control on the casino floor? Have you felt the near-miss buzz or the comfort of those stop buttons? 

Share your stories in the comments below—let’s outsmart the illusion together.

Mashable is a global, multi-platform media and entertainment company
For more queries and news contact us on this
Email: info@mashablepartners.com